Study: Are the Nutrients in Multivitamin Supplements Absorbed?
A nine-year longitudinal clinical study from the University of Parma, Italy found that taking multivitamins can result in measurably higher levels of nutrients, especially for those who show shortfalls in nutrition levels.
About the Study
The study, "Effects of Multivitamin/Mineral (MVM) Supplementation on Plasma Levels of Nutrients," (nutrient absorption study),1 a secondary publication based on a major NIH-funded human clinical trial,2 reveals the real long-term benefits of taking a daily multivitamin.
The study investigates how long-term multivitamin/multimineral supplementation affects not only riboflavin status, but also plasma (blood) levels of vitamins A, B12, C, E, beta-carotene, and folic acid. Participants were all healthy, well-nourished adults aged 55-75 years who randomly received either a Centrum3 or a placebo tablet daily.
The Centrum tablet provided essential vitamins and minerals at or about the daily recommended levels as established by the National Academy of Medicine and adopted by the U.S. Food and Drug Administration.
- Effects of Multivitamin/Mineral Supplementation on Plasma Levels of Nutrients: Report No.4 of the Italian-American Clinical Trial of Nutritional Supplements and Age-Related Cataract. Annali dell’Istituto Superiore di Sanità; 45: 119-127.
- A Randomized, Double-Masked, Placebo-Controlled Clinical Trial of Multivitamin Supplementation for Age-Related Lens Opacities: Clinical Trial of Nutritional Supplements and Age-Related Cataract; Report No.3. Ophthalmology 2008; 115: 599-606.
- Pfizer Consumer Healthcare provided the Centrum tablets used in the nine-year study, but played no role in the collection, analysis or interpretation of the data or preparation of the study manuscript.