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Centrum Silver is clinically shown to slow biological aging*

To learn more about biological aging and the latest research, read below.

Biological aging

When you think about aging, you probably think about your birthday. But what if the number of candles on your cake doesn’t tell the whole story? Biological aging refers to how well your cells and systems are functioning over time, which may differ from your chronological age (the number of years you’ve lived). Two people who are the same chronological age may have different biological ages due to differences in genetics, lifestyle, and overall health. For older adults, this concept can feel especially meaningful. Healthy aging isn’t just about adding years, it’s about maintaining vitality and overall well-being.

About the Study

New research findings published in Nature Medicine come from an analysis of the large-scale COSMOS (COcoa Supplement and Multivitamin Outcomes Study) clinical trial. In this analysis of nearly 1,000 adults in their 60s and 70s followed for two years, participants who took a daily multivitamin (Centrum Silver) had statistically significantly slower increases in two epigenetic clocks compared to those taking a placebo. Researchers estimate the difference equated to about four months less biological aging over two years.  Researchers also observed that the effects were stronger in participants who were aging faster biologically at the start of the study.

What does this mean for healthy aging?


Scientists use advanced DNA-based tools called “epigenetic clocks” to help estimate how quickly the body is aging on a cellular level. These tools are still evolving, but they help researchers better understand how everyday habits, including nutrition, may influence how we age. While the findings do not suggest that multivitamins stop or reverse aging, they offer evidence into how a daily multivitamin like Centrum Silver may  support healthy aging at a cellular level.  Because Centrum Silver is a once-daily multivitamin that is widely available and affordable, this research highlights a simple, accessible step older adults can consider as part of their overall healthy aging routine.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Taking Centrum Silver daily may slow cognitive aging* up to 60%

To learn more about cognitive aging and the COSMOS-Mind study, read below

For Your Body’s Needs

Cognitive Aging


Cognitive health
—the ability to think, learn, and remember—is an important part of healthy aging. Mild changes over time are a normal part of the process. Why might a multivitamin help? As we age, our diets often change, and older adults are more likely to have shortfalls in essential vitamins and minerals. Multiple vitamins and minerals—including B vitamins, zinc, and others—are important for supporting normal brain health and cognitive function.

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About the Study


COSMOS-Mind was a large, gold standard clinical trial conducted by leading researchers at Wake Forest University School of Medicine and Brigham and Women’s Hospital, Harvard Medical School, and the Harvard T.H. Chan School of Public Health. The study followed 2,262 healthy women and men aged 65+ for 3 years, looking at daily multivitamin use and cognitive function. Centrum Silver was the multivitamin used in the trial. People taking the multivitamin did better on thinking and memory tests than those taking a placebo.

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What did the study measure and how was it made clinically relevant?


The study measured changes in thinking and memory using a set of tests over three years. To make sense of the results, researchers used statistical modeling to separate the effects of the multivitamin from normal aging and practice effects. They estimated that taking Centrum Silver daily for 3 years may slow the rate of cognitive aging by about 60%, which is roughly 1.8 “years” of protection over 3 years.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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For Your Body’s Needs

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*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.