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Latest Research Reinforces the Power of Centrum Silver Multivitamins for Cognitive Health

March 2024
New study results from the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) offers additional evidence regarding the benefit of Centrum Silver multivitamin tablets on cognitive health in older adults. The 3rd independent cognition trial to measure cognitive function and memory in older adults echoed previous findings of COSMOS-Mind and COSMOS-Web which all indicate that daily use of Centrum Silver versus a placebo resulted in significant improvements in performance on tests measuring memory.

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What’s New?

In January of 2024, the third COSMOS cognition trial results were published by researchers from Harvard Medical School and Brigham and Women’s Hospital. Detailed information about the prior two studies can be found here and here.

This latest study included a group of over 500 older men and women (60+ years) who were randomized to receive either Centrum Silver Multivitamin tablets or a placebo (a pill with no active ingredients). They completed in-person cognitive assessments at the beginning of the trial and then every year for 2 years. The tests measured their overall cognitive function (a variety of mental activities used in everyday life such as attention, language, processing speed, etc.), as well as memory and executive function (things like decision making, planning, and problem solving). After looking at the data over 2 years, the researchers found that people who took Centrum Silver Multivitamin tablets had greater performance on the memory tests than those taking the placebo.

In addition to this new evidence, the COSMOS researchers also looked at the combined data across all three of their cognition studies (over 5,000 non-overlapping participants), each which measured cognitive function & memory among older adults in slightly different ways (by telephone, computer or in-person). When looking at the data across all three studies, there was clear and consistent benefits to daily use of Centrum Silver Multivitamin tablets on cognitive function and memory.

The Big Picture

A healthy, balanced diet is important for good health. However, as we age our nutrient needs change and older adults often fall short of meeting recommended amounts of key vitamins and minerals. Adding a multivitamin like Centrum Silver can be a practical and helpful strategy to fill those dietary gaps and support overall health. And as the COSMOS research shows, it can also support memory and cognition as you age - just another benefit to adding a multivitamin to your wellness routine.

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

  • Show References

    1. Vyas CM, Manson JE, Sesso HD, et al. Effects of multivitamin-mineral supplementation versus placebo on cognitive function: Results from the clinic sub-cohort of the COSMOS randomized clinical trial and meta-analysis of three cognitive studies within COSMOS. Am J Clin Nutr. Published online Jan 18, 2024.
    2. U.S. Department of Agriculture and U.S. Department of Health and Human Services. Dietary Guidelines for Americans, 2020-2025. 9th Edition. December 2020. Available at

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